Munoz-Rodriguez JM, Lopez-Monclus J, Mendez CSM, et al. - Researchers conducted a multicenter study with the aim at determining the operative and patient-reported outcomes in patients who presented with the combination of midline and lateral incisional hernia and were managed with using a modified posterior component separation. A prospective, multicenter database yielded data from 58 patients who underwent operative repairs of a midline and lateral incisional hernia at 4 centers with minimum 2-year follow-up. The operative techniques employed were transversus abdominis release in 26 patients (45%), a modification of transversus abdominis release in 27 (47%), a reverse transversus abdominis release in 3 (5%), and a primary, lateral retromuscular preperitoneal approach in 2 (3%). The different techniques resulted in acceptable results, despite the associated high complexity. A clinically important improvement in quality of life and pain was achieved as per patient-reported outcomes after measurement of the European Registry for Abdominal Wall Hernias Quality of Life score.