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Outcomes associated with the use of medications for opioid use disorder during pregnancy

Addiction Jun 01, 2021

Krans EE, Kim JY, Chen Q, et al. - Researchers conducted a retrospective cohort analysis of claims, encounter, and pharmacy data with the aim to determine if the duration of medication for opioid use disorder (MOUD) use during pregnancy affects maternal, perinatal, and neonatal outcomes. Analysis was performed including 13,320 pregnancies among 10,741 women with opioid use disorder aged 15-44 years who were enrolled in Pennsylvania Medicaid between 2009 and 2017. Among these pregnancies, 306 (2.3%) were complicated by an overdose, 1,753 (13.2%) resulted in a preterm birth and 6,787 (50.9%) continued MOUD postpartum. Findings indicated correlation of longer duration of medication for opioid use disorder use during pregnancy with improved maternal and perinatal outcomes.

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