Outcomes and risk factors for cardiovascular events in hospitalized COVID-19 patients
Journal of Cardiothoracic and Vascular Anesthesia Mar 31, 2021
Xu Q, Samanapally H, Nathala P, et al. - Researchers aimed at determining outcomes and risk factors of cardiovascular events in a metropolitan COVID-19 database. In addition, they performed a subgroup analysis in African American populations to assess if outcomes and risk factors are influenced by race. In this population-based study conducted in Louisville, KY, USA, they assessed 700 adult inpatients hospitalized with COVID-19. This cohort comprised 126 patients (18%) with cardiovascular events and 574 patients without cardiovascular events. Findings suggest the prevalence of cardiovascular events and their correlation with worse outcomes in hospitalized patients with COVID-19. After propensity score matching analysis, they identified similar outcomes of cardiovascular events in African American and white COVID-19 patients. African American COVID-19 patients exhibited common as well as unique risk factors for cardiovascular events when compared with white patients. In COVID-19 patients, the occurrence of cardiovascular events was observed in marked correlation with male gender, race, lower SaO2/FiO2, higher serum potassium, lower serum albumin, and number of cardiovascular co-morbidities. For African American COVID-19 patients, marked correlation of lower serum albumin and neoplastic/immunocompromised diseases with cardiovascular events was observed. In white patients, SaO2/FiO2 ratio and cardiovascular comorbidity count were significantly linked with cardiovascular events.
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