Lerch D, et al. - In this retrospective case series, researchers described the technique of sub-Tenon’s anesthesia and reported adverse events and patient comfort. In a large population of patients undergoing refractive lens exchange or cataract surgery, they described the own technique with the use of a flexible cannula and present adverse events and patient comfort. They retrospectively reviewed the outcomes of 35,850 intraocular procedures (phacoemulsification and implantation of an intraocular lens) and measured the incidence of adverse events related to sub-Tenon’s anesthesia. The anesthetic solution comprised of a mixture of Lidocaine and Hyaluronidase, which was administered into sub-Tenon’s space with a single-use sterile polyurethane 22G x 1” (0.9 x 25 mm) cannula. According to findings, no significant adverse events have been reported that would impact the posterior segment of the eye or result in vision loss. In 4.3% of eyes, subconjunctival haemorrhage associated with sub-Tenon’s anesthesia was reported. Findings suggested that sub-Tenon’s anesthesia is a safe option for ophthalmic anesthesia with the use of a flexible cannula.