Timor-Tritsch I, Buca D, Di Mascio D, et al. - Given that the link between the most severe types of placenta accreta spectrum disorders and caesarean scar pregnancy (CSP) raises the question if early diagnosis may influence the clinical result of these anomalies, therefore, researchers analyzed the outcome of CSP diagnosed in the early (≤ 9 weeks) compared with late (> 9 weeks) first trimester of pregnancy. By exploring Medline, Embase and Clinicaltrail.gov databases, relevant studies were identified. Findings revealed a significantly lower risk of maternal complications in relation to early first trimester diagnosis of CSP, therefore lending support to a policy of universal screening for these anomalies in females with a prior cesarean delivery although future studies should be conducted to assess the cost-effectiveness of such policy.