• Profile
Close

Outcome measures used in psoriatic arthritis registries and cohorts: A systematic literature review of 27 registries or 16,183 patients

Seminars in Arthritis and Rheumatism Jun 24, 2021

Aouad K, Moysidou G, Rakotozafiarison A, et al. - Multiple outcome measures can be employed to assess disease activity in psoriatic arthritis (PsA), which is a multidimensional inflammatory disease. The first core domain set in PsA was proposed by the OMERACT in 2006. Researchers herein assessed outcome measures obtained in recent PsA registries or longitudinal cohorts. A systematic literature review, performed in Pubmed Medline yielded 673 articles; 73 of these were included in the analysis, reporting on 27 registries/cohorts. Overall, they included 16,183 patients, with a mean of 599 per study; 51% were men, weighted mean age was 49.7±9.3 years and weighted mean disease duration was 6.8±0.2 years. Great heterogeneity was observed in data collection in PsA, reflecting the necessity for international consensus on outcome measures. They obtained 58 different outcome measures. In 20/27 (74%) registries, disease activity composite scores were utilized through 8 different scores (most frequently Minimal Disease Activity: 41%, DAS28: 33% and DAPSA: 30%). Among the domains of PsA, 26/27 (96%) registries described joint involvement (through the 66/68 joint count: 85%) and 93% described skin psoriasis (through PASI: 72%), whereas enthesitis, dactylitis and axial involvement were less often described (respectively, 77%, 74% and 52%). In addition, 22/27 (82%) studies documented HAQ; patient global assessment (70%) and pain (63%) were the other frequently reported PROs.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay