Zawawi F, Shapiro AJ, Dell S, et al. - Researchers conducted this cross-sectional study to prospectively and objectively evaluate otolaryngological manifestations and quality of life of children with primary ciliary dyskinesia (PCD) and compare these findings with healthy pediatric controls. The sample consisted of 47 children with PCD and 25 control participants. Upper airway symptoms were more common in PCD children than in healthy children. They had significantly higher scores in both Sino-Nasal Outcome Test 22 and Reflux Symptom Index, implying worse sinonasal and reflux symptoms, with worse quality of life on the Hearing Environment and Reflection Quality of Life index compared with healthy children. Staphylococcus aureus was the most common bacteria cultured from the middle meatus in 11 of 47 (23%), followed by Streptococcus pneumoniae in 10 of 47 (21%). The importance of otolaryngology involvement in the management of children with PCD is highlighted by this multisite cohort. More stringent otolaryngological management may result in lower overall morbidity and improved quality of life in children with PCD.