Patel A, et al. - Researchers identified fracture risk in patients with cirrhosis, specific risk factors, and the effect of fractures on health care use by analyzing data from a national database. To examine fracture-related hospitalizations of patients with cirrhosis using the National Inpatient Sample from 2012 to 2013, an observational study using serial cross-sectional data was conducted. To determine risk factors for fracture and fracture-related mortality, multivariate regression was used. Cirrhosis and osteoporotic fracture patients had an average length of stay (LOS) of 10.4 days and incurred $26,582 per hospitalization, which was statistically different from non-cirrhotic fracture patients and cirrhotic patients without fracture. Findings revealed that hospitalizations in patients with cirrhosis for osteoporotic fractures are an important source of the burden of health care and mortality. Malnutrition is related to increased risk of fracture and mortality associated with fracture, which is a modifiable risk factor worthy of treatment in patients with cirrhosis. Outcomes suggested that screening patients with cirrhosis for low bone mass should be given more attention.