Osteoarthritis development related to cartilage quality-the prognostic value of dGEMRIC after anterior cruciate ligament injury
Osteoarthritis and Cartilage Aug 08, 2019
Tjörnstrand J, et al. - Thirty-one patients with anterior cruciate ligament injury were analyzed following 2 years with 1.5T Delayed Gadolinium-enhanced MRI of cartilage (dGEMRIC) of femoral cartilage by the researchers in order to examine the prognostic value of the dGEMRIC index regarding future knee osteoarthritis (OA). In comparison with those that did not develop ROA, SOA or poor function, the dGEMRIC index of the medial compartment was lower in knees that developed medial ROA. Radiographic OA (ROA) was present in 68% and OA symptoms (SOA) in 42% of the injured knees at the 14-year follow up. In medial and lateral compartments, the dGEMRIC index associated negatively with the OARSI osteophyte score. Hence, the relationships between a low dGEMRIC index and future ROA, as well as SOA, were in agreement with former studies and exhibited that dGEMRIC had a predictive value for future knee OA.
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