Oropharyngeal squamous cell carcinoma induces an innate systemic inflammation, affected by the size of the tumour and the lymph node spread
Clinical Otolaryngology Jun 03, 2018
Kågedal A, et al. - Experts ascertained the systemic inflammation in patients with oropharyngeal squamous cell carcinoma (OPSCC) and gauged its relation to tumour size, ability to metastasise and HPV status. Findings suggested an increased systemic inflammation in patients with OPSCC. This inflammation was seen to be affected by the HPV status, the size of the tumour and lymph node spread. An increased number of neutrophils and monocytes was seen in the patients with OPSCC, whereas the lymphocytes were suppressed vs the healthy controls.
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