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Oropharyngeal hemorrhage in patients with COVID-19: A multi-institutional case series

American Journal of Otolaryngology - Head and Neck Medicine and Surgery Aug 22, 2020

Mulcahy CF, Ghulam-Smith M, Mamidi IS, et al. - Researchers sought to describe the clinical course of five cases of oropharyngeal hemorrhage in COVID-19 patients on mechanical ventilation requiring evaluation by otolaryngologists at George Washington University Hospital (GWUH) and Boston Medical Center (BMC) from March to April 2020. Conservative management was undertaken in all five patients; four needed packing with Kerlix gauze by an otolaryngologist. Extracorporeal membrane oxygenation (ECMO) and associated anticoagulation were required, in addition, for two patients. Oropharyngeal packing led to improvement in three patients; persistent bleeding was observed in two. Death of three patients was observed. Less frequent repositioning of endotracheal tubes was done due to the COVID-19 pandemic. These observations suggest an increased risk of oropharyngeal hemorrhage in intubated patients with COVID-19, which might be due to anticoagulation, prolonged intubation, or decreased frequency of endotracheal tube repositioning.

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