Kashyap D, Baral B, Verma TP, et al. - In view of the known role of Helicobacter pylori (H. pylori) in chronic gastritis and gastric cancer, researchers here emphases the isolation of H. pylori from distinct habitats of the gut microenvironment (gastric biopsy and gastric juice) and its subsequent characterization. Further, they evaluated how various oral rinses affects isolated H. pylori from different anatomical locations of included individuals. Observations revealed a striking difference in the growth pattern of the possible strains isolated from two different habitats of the same individual. The use of oral rinses led to the downregulation of the expression of H. pylori pathogenic gene (CagA). Hence, the H. pylori in the oral cavity and its migration from oral to the gastric compartment could be reduced with oral rinses. Oral rinses may be used as an adjuvant treatment option for its re-infection.