Ribeiro JL, Moraes RM, do Carmo Carvalho BF, et al. - In this study, clinical, microscopic, and immunohistochemical features of the two types of oral Pyogenic granuloma (PG): lobular capillary hemangioma (LCH) and non‐LCH (NLCH) were compared. Between 2000 and 2018, researchers obtained epidemiological and clinical data from the archives of our institution, and histopathological sections of PG were reviewed. Immunohistochemical analyses (CD34, D2‐40, SMA, mast cell, and Ki‐67) were performed in 34 cases. The study enrolled a total of 62 LCH and 107 non‐LCH samples. The data exhibited that PG accounted for 2.25% of lesions archived in the pathology service and most cases were NLCH. According to the findings, LCH and NLCH showed clinicopathological variations in terms of age, site, epithelial atrophy, vascularization, and proliferation rate.