Cervenka I, et al. - Considering the conflicting findings of studies assessing the association between oral contraceptive (OC) use and melanoma risk, researchers analyzed E3N (a prospective cohort of 98,995 French women aged 40–65 years at inclusion in 1990) on these associations. Starting in 1992, exposure to lifetime OC use was assessed via biennial questionnaire updates. Over 1992–2008, they recognized 539 melanoma cases among 79,365 women. Age-adjusted models revealed a modest positive correlation between ever use of OCs and risk of melanoma, which was lower following adjustment. Among long-term users and women who used high-estrogen OCs, a stronger correlation was seen. Still, no strong association between OC use and melanoma risk was found overall. Findings suggest intentional ultraviolet (UV) exposure in OC users supports a potential confusion by UV exposure in this relationship.