van den Heuvel MEN, et al. - This trial incorporated an evaluation of the effect of different pulse oximetry (SpO₂) target range settings during automated fraction of inspired oxygen control (A-FiO₂) on time spent within a clinically set SpO₂ alarm range in oxygen-dependent infants on noninvasive respiratory support. Researchers drew the conclusion that narrowing the target range of A-FiO₂ to the desired median ±2% appeared to be effective in reducing the time spent in hypoxemia, without increasing the risk of hyperoxemia.