Russo JJ, et al. - The optimal mean arterial pressure (MAP) was determined during the early-to-intermediate phase care of comatose survivors of out-of-hospital cardiac arrest (OHCA). Researchers noted higher area below pre-specified MAP thresholds (ABT; mmHg*hours) to be associated with increased rates of severe neurological dysfunction when MAP thresholds <75 mmHg are used in comatose survivors of OHCA with an initial shockable rhythm. The hypothesis that higher MAP targets (≥75 mmHg) may be indicated in this patient population was here supported by the findings.