Yonemoto K, et al. - A single-center, retrospective observational study was conducted in Japan to illustrate whether H1 antihistamine administration increases susceptibility to febrile convulsions in children. From 2011 through 2016, three hundred eighty children with febrile convulsions between the ages of 6 months and 5 years transported via ambulance were included. In children who received H1 antagonists, prolonged seizure duration and shortened interval from fever to seizure were not observed. Results of this study suggested that H1 antagonists at optimal doses could be safely used in febrile children with allergic symptoms.