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Optimal cutoff values of fasting plasma glucose (FPG) variability for detecting retinopathy and the threshold of FPG levels for predicting the risk of retinopathy in type 2 diabetes: A longitudinal study over 27 years

Diabetes Research and Clinical Practice Apr 09, 2018

Takao T, et al. - The authors aimed at assessing the cutoff values of fasting plasma glucose (FPG) variability for detecting retinopathy and examining the threshold of FPG levels for predicting retinopathy incidence in type 2 diabetes. They proposed new cutoff value for FPG standard deviation (SD) (1.4 mmol/L) to detect retinopathy. Compared to the guideline targets, cutoff values of FPG and HbA1c were slightly higher. To predict future retinopathy in diabetes, FPG threshold (6.9 mmol/L) is proposed. They noted that retinopathy risk in the next 25 years rose sharply from FPG level of 7.4 mmol/L. Younger and female patients with type 2 diabetes showed increased retinopathy risk.
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