Sleiman K, et al. – A prospective, longitudinal study is carried out to devolp spectral–domain optical coherence tomography (SD OCT)–based risk assessment models for the 5–year new onset of geographic atrophy (GA) and central GA on color photography (CP). For age–related macular degeneration (AMD) eyes with large drusen and no advanced disease, they built a novel risk assessment model—based on age and SD OCT segmentation, drusen characteristics, and retinal pathology—for progression to CP–visible GA over up to 5 years. This calculator may simplify SD OCT grading and with future validation has a promising role as a clinical prognostic tool.