Kim M, Lee YJ, Park W, et al. - In this consecutive observational case series, researchers identified the optical coherence tomography biomarkers that can collectively predict the probability of collapse or reduction of drusenoid pigment epithelium detachment (PED). They reviewed the clinical data of 24 eyes with non-neovascular drusenoid PED. Among the study population, 17 eyes displayed collapse or reduction of drusenoid PED. After PED reduction and during the most recent visit, the mean subfoveal choroidal thickness showed a substantial decrease. Migration of retinal pigment epithelium cells was identified in 15 (88.2%) after PED reduction, however, the frequency of migration of retinal pigment epithelium cells at each point of time was not important. Evidence of non-neovascular subretinal fluid and choroidal thinning was found prior to PED reduction. This finding may be useful for detecting and predicting the progression of drusenoid PED.