Zur D, et al. - The topic under exploration here was the optical coherence tomography (OCT) biomarkers for diabetic macular edema (DME) treated by intravitreal dexamethasone (DEX) implant. The findings unveiled that spectral-domain OCT was beneficial in determining several imaging findings in DME. Among eyes with DME, those with submacular fluid, no HRF, and a continuous IS-OS layer responded better to DEX implants than those without these features. These findings call for further study of combinations of OCT and metabolic biomarkers.