Nagendra D, Sonalkar S, Schurr D, et al. - This study was sought to correlate the overnight maximum pain scores after osmotic dilator placement prior to a dilation and evacuation (D&E) procedure in participants assigned to a prescription for ibuprofen alone or to ibuprofen plus oxycodone. Researchers performed a nonblinded pragmatic, randomized controlled trial to assess pain management among women undergoing osmotic dilator placement prior to D&E. Researchers randomized a total of 70 participants at 12 weeks 6 days to 23 weeks 6 days gestation to receive a prescription for ibuprofen alone, or ibuprofen plus oxycodone. The results of this study demonstrate that in comparison with participants randomized to receive a prescription for ibuprofen, those randomized to receive a prescription for ibuprofen plus oxycodone reported higher maximum overnight pain scores.