Ophthalmic artery doppler in combination with other biomarkers in the prediction of pre‐eclampsia at 35–37 weeks’ gestation
Ultrasound in Obstetrics & Gynecology Oct 22, 2020
Sarno M, Wright A, Vieira N, et al. - This study was undertaken to investigate the potential value of maternal ophthalmic artery Doppler at 35‐37 weeks’ gestation in combination with the established biomarkers of preeclampsia, including mean arterial pressure, uterine artery pulsatility index, serum placental growth factor and serum soluble fms‐like tyrosine kinase‐1, in the prediction of subsequent development of preeclampsia (PE). Researchers conducted a prospective observational study in women attending for a routine hospital visit at 35+0 ‐ 36+6 weeks’ gestation. A 2,287 pregnancies were included containing 60 (2.6%) that developed PE, including 19 (0.8%) that delivered with PE at < 3 weeks from the evaluation. At 35‐37 weeks, ophthalmic artery Doppler could potentially improve the performance of screening for PE, particularly imminent PE with delivery within three weeks of evaluation, but further trials are required to confirm this finding.
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