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Open-label, multicentre, dose-escalating phase II clinical trial on the safety and efficacy of tadekinig alfa (IL-18BP) in adult-onset Still’s disease

Annals of Rheumatic Diseases Mar 09, 2018

Gabay C, et al. - Experts assessed whether interleukin (IL)-18 inhibition, using the recombinant human IL-18 binding protein, tadekinig alfa, is a therapeutic option in adult-onset Still’s disease (AOSD). As per findings, tadekinig alfa appeared to have a favourable safety profile and was related to early signs of effectiveness in patients with AOSD.
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