Johns BP, Loewenthal MR, Davis JS, et al. - In this study, the outcomes of open vs arthroscopic debridement of infected total knee arthroplasty (TKA) were compared. Between 2002 and 2017, researchers examined 141 patients at a university teaching hospital with an infected TKA treated with debridement, antibiotics, and implant retention (DAIR). The primary endpoint included successful treatment defined by applying international consensus criteria. Antibiotic suppression, prosthesis retention, mortality, postoperative range of motion, and length of stay were considered as secondary endpoints. They obtained clinical, laboratory, surgical, and antibiotic treatment data. They further conducted a propensity score matching to control for selection bias. In comparison with arthroscopic DAIR. open DAIR is a more successful index procedure for infected TKA. The data revealed that open DAIR remained more successful even when antibiotic suppression is considered successful treatment.