Sun F, Wang H, Zhang D, et al. - For lupus patients with acute kidney injury (AKI), a more accurate management might be facilitated by applying the predictive nomogram models proposed in this study.

• This study included 130 and 96 patients with lupus AKI in the derivation and validation cohorts, of which 82 and 73 patients received renal biopsy, respectively.

• Determinants of SLE duration, days from AKI onset to treatment and baseline creatinine level were incorporated into the prognostic nomogram model without pathology (C-index 0.85 and 0.79 for the 2 cohorts).

• An incremental predictive performance, in derivation but not in validation cohort, was achieved by combining histologic interstitial tubular fibrosis in the nomogram (C-index 0.93 vs 0.85 in derivation and 0.81 vs 0.79 in validation cohorts).

• The prediction models are clinically beneficial, by decision curve analysis.