Vlieger S, Danzi GB, Kauer F, et al. - Researchers compared a newer generation thin-strut cobalt chromium sirolimus-eluting coronary stent (SES, Ultimaster) to a second-generation thicker strut stainless steel biolimus-eluting stent (BES, Nobori) in percutaneous coronary intervention (PCI) practice, here focusing on safety and efficacy. From two PCI registries (e-Ultimaster and NOBORI 2), a total 8137 SES patients and 2738 BES patients were selected and a propensity score analysis was applied to adjust for differences in baseline features. A significantly lower rate of myocardial infarction (MI) and target vessel-related MI was observed at 1 year in relation to use of SES vs BES. According to the findings of this study, a newer generation thin-strut SES provided an improved clinical safety as well as efficacy relative to a second-generation thicker strut BES.