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One-hour oral glucose tolerance test plasma glucose at gestational diabetes diagnosis is a common predictor of the need for insulin therapy in pregnancy and postpartum impaired glucose tolerance

Journal of Diabetes Investigation May 04, 2018

Nishikawa T, et al. - Researchers examined the predictors of the need for insulin therapy in gestational diabetes mellitus (GDM) patients. Furthermore, they analyzed the predictors of postpartum impaired glucose tolerance (IGT). Findings illustrated gestational weeks at GDM diagnosis and history of pregnancy were considerably lower, and pregestational body mass index, family history of diabetes mellitus, 1- and 2-h glucose levels in a 75 g oral glucose tolerance test (OGTT), the number of abnormal values in a 75 g OGTT, and glycated hemoglobin were significantly higher in participants receiving insulin therapy. It was inferred that antepartum 1-h glucose levels in a 75 g OGTT presented as a predictor of the need for insulin therapy in pregnancy and postpartum IGT.
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