Imboden S, et al. - Given the controversy about the extent of lymph node removal that is needed in endometrial cancer, researchers examined oncological safety and perioperative morbidity in low-risk endometrial cancer (FIGO Stage 1, endometrioid histology, Grades 1 and 2) with sentinel lymph-node dissection. Analyzing perioperative data and oncological outcome in this retrospective comparative study on low-risk endometrial cancer, they compared and assessed the extent of surgical lymph-node assessment (no lymphadenectomy vs removal vs lymphadenectomy) in two European institutions. Among the included 279 patients, 103 (36.9%) had no lymphadenectomy, 118 (42.3%) underwent SLN removal, and 58 (20.8%) had pelvic and/or para-aortic lymphadenectomy. As per findings, a convincing balance between oncological safety and perioperative morbidity was achieved with sentinel lymph node removal in early-stage, endometrial cancer, Grade 1 and 2. They identified lymph-node evaluation in any form as crucial especially in LVSI-positive cases.