Özgen IT, et al. - Given an important role of adipokines in the pathogenesis of polycystic ovarian syndrome (PCOS) and the omentin, an adipokine secreted essentially by visceral adipose tissue, has an insulin-sensitizing effect, researchers investigated omentin-1 level in adolescent girls with PCOS and its correlation with insulin resistance (IR), a common feature of PCOS, and androgens. In the study, they enrolled a total of 41 obese girls with PCOS, and 30 age- and body mass index (BMI)-matched obese girls without PCOS. Compared to the control group, the PCOS group displayed higher homeostatic model assessment of IR (HOMA-IR), free and total testosterone but lower omentin-1. Omentin-1 showed an inverse correlation with free testosterone and BMI standard deviation score (BMI-SDS) but it was not identified to be correlated with total testosterone, HOMA-IR, glucose, insulin or serum lipids.