Sibille KT, et al. - On the basis of recommended and typical ranges of the omega-6 (n-6):omega-3 (n-3) ratio, researchers investigated if in adults with knee pain, those with a high n-6:n-3 ratio would have greater pain/functional limitations, experimental pain sensitivity, and psychosocial distress compared with those with a low n-6:n-3 ratio. Findings illustrate an association of a high n-6:n-3 ratio with greater clinical pain/functional limitations, experimental pain sensitivity, and psychosocial distress.