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Occupational exposures and male breast cancer: A nested case-control study in the Nordic countries

The Breast Nov 20, 2019

Talibov M, Hansen J, Heikkinen S, et al. - Within the large Nordic Occupational Cancer Study, researchers assessed male breast cancer (MBC) in relation to solvents, metals, exhaust gases and other agents. A total of 1,469 MBC cases and 7,345 controls recruited from Finland, Iceland and Sweden, matched for the date of birth, gender and country, were analyzed. Using national cancer registries, they selected cases. They evaluated 24 occupational exposures. For physical workload, a significantly reduced overall OR was reported. For trichloroethylene, iron, lead, chromium, welding fumes, and wood dust, they observed non-significantly raised ORs. For asbestos, silica dust and perchloroethylene, they observed reduced ORs. Overall, findings revealed a 20–25% protective influence for physical workload at work. For other agents, no strong proof was obtained.
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