Stojanovic J, et al. - The current knowledge on the relationship between genetic polymorphisms, occupational exposures, and urinary tract cancers was summarized via searching MEDLINE, ISI Web of science, and SCOPUS online databases for all English language articles published up to September 2016. Findings suggest a possible association between the variant genotypes of GSTM1, GSTT1, NAT2 and SULT1A1, occupational exposure to aromatic amines or polycyclic aromatic hydrocarbons, and development of breast cancer. In individuals occupationally exposed to pesticides, polymorphisms in GSTM1 and GSTT1 genes might influence the risk for developing kidney cancer.