Occult blood in feces is associated with an increased risk of ischemic stroke and myocardial infarction: A nationwide population study
Journal of the American Heart Association Jan 07, 2021
Moon JM, Lee HJ, Han K, et al. - Researchers utilized the National Health Insurance database to assess the clinical utility of fecal immunochemical test (FIT) in patients suffering from cardiovascular diseases (ischemic stroke and myocardial infarction [MI]). Screening as well as follow-up was performed among participants (aged > 50 years) with colorectal cancer (CRC) screening records from 2009 to 2012. This study involved 6,277,446 eligible individuals. In a multivariate‐adjusted model, a higher risk of ischemic stroke was observed in the FIT‐positive population, as was a raised risk of MI and increased all‐cause death. Overall, findings demonstrated an association of positive FIT findings with ischemic stroke, MI, and mortality. Experts suggested more clinical information may be afforded by occult blood in feces than its well‐known conventional role in CRC screening.
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