Wang S, et al. - In 130 consecutive patients with a confirmed diagnosis of hypertrophic obstructive cardiomyopathy (HOCM), the link between non-sustained ventricular tachycardia (NSVT) and obstructive sleep apnea (OSA) was examined using polysomnography and Holter electrocardiography. A total of 130 patients were included, OSA was diagnosed in 72 (55.4%), including 38 with mild, 21 with moderate, and 13 with severe OSA, and NSVT was present in 27 (20.8%) patients. With the severity of OSA, an increased prevalence of NSVT was noted (none, mild, moderate, and severe: 12.1%, 15.8%, 33.3%, and 53.8%, respectively). Among the different OSA groups, a remarkably higher apnea-hypopnea index (AHI) was seen in patients with NSVT vs those without NSVT. After adjustment for age, sex, and body mass index, the only factors that demonstrated relation to NSVT were family history of HCM or sudden cardiac death (SCD) and AHI. Overall, findings showed an independent association of the presence and severity of OSA with NSVT, which is a risk factor for SCD and cardiovascular death in this population.