Tenaw Z, et al. - Analysts evaluate knowledge, practice and related factors of obstetric care providers (Midwives, Nurses and Health officers) on active management of the third stage of labor in Sidama Zone, South Ethiopia. The knowledge and practice of obstetric care providers towards the active management of the third stage of labor can be improved with appropriate interventions like in-service training. This study also clearly demonstrated that the level of knowledge and practice of obstetric care providers to wards active management of the third stage of labor needs immediate attention of Universities and health science colleges better to revise their obstetrics course contents, health institutions and zonal health bureau ought to arrange training for their obstetrics care providers to enhance skill.