Obesity paradox in the era of percutaneous coronary intervention with 2nd-generation drug-eluting stents: An analysis of a multicenter PCI registry
Heart and Vessels Aug 03, 2018
Ueshima D, et al. - Researchers used a multicenter registry to determine the impact of overweight status (defined as body mass index > 25 kg/m2) on adverse events in patients who had everolimus-eluting stent (EES) implantation with a maximum follow-up of 3 years. They performed propensity score matching for adjusting baseline characteristics. They found that even when excluding non-cardiac mortalities, better outcomes for major adverse cardiac and cerebrovascular events (MACCE: a composite of mortality from all causes, nonfatal myocardial infarction, and nonfatal stroke) were demonstrated by overweight patients. With regard to secondary prevention of cardiovascular events, no advantage to non-overweight EES-implanted patients was seen.
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