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Obesity may enhance the adverse effects of NO2 exposure in urban schools on asthma symptoms in children

The Journal of Allergy and Clinical Immunology Mar 23, 2020

Permaul P, Gaffin JM, Petty CR, et al. - Via involving students aged 4-13 years with asthma from 37 inner-city schools, researchers explored the connections between classroom NO2 exposure and asthma symptoms and morbidity by BMI category. In total, 271 predominantly Black or Hispanic students were involved in analyses. According to The School Inner-City Asthma Study, obese BMI status seems to increase susceptibility to classroom NO2 exposure impacts on asthma symptoms in inner-city children. Environmental interventions that target indoor school NO2 levels can improve the health of obese children with asthma. While the results after adjustment for multiple comparisons will not remain statistically important, the large effect sizes warrant future analysis of the role of obesity and pollution in pediatric asthma.

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