Obesity Is Associated with Earlier Pubertal Onset in Boys
Journal of Clinical Endocrinology & Metabolism Mar 17, 2020
Busch AS, et al. - Researchers investigated if and how male pubertal timing is associated with age-specific BMI (zBMI) in obese boys. From 2009 to 2017, recruitment of a total of 218 obese boys (zBMI > +2SD, with a median age at baseline of 10.8 years (range 4.2–17.0), was done as part of a prospective outpatient childhood obesity intervention program at Nordsjællands Hospital, Hillerød, Denmark. Six hundred sixty healthy boys participating in the population-based COPENHAGEN Puberty Study (-2SD < zBMI ≤ +2SD, 2006–2014) were assessed as controls in this study. The participants were assessed for timing of testicular volume ≥ 4 mL, genital stage ≥ 2, and pubarche. As per outcomes, obese boys exhibit testicular enlargement significantly earlier compared with a population-based normal-weight reference cohort.
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