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Obesity, comorbidities, and treatment selection in Black and White women with early breast cancer

Cancer Dec 11, 2020

Nyrop KA, Damone EM, Deal AM, et al. - Researchers conducted this retrospective chart review to examine obesity and comorbidity in Black and White women with early breast cancer (stages I‐III) and their potential effect on treatment decisions for patients with hormone receptor–positive (HR+)/human epidermal growth factor receptor 2–negative (HER2–) tumors. Comparisons of frequencies were determined with the Fisher exact test for Black and White patients. In a study of 548 patients, 26% were Black and 74% were White. Data reported that 62% of Black patients and 32% of White patients were obese (BMI ≥ 30 kg/m2). It was noted that 75% of Black patients and 87% of White patients had HR+ tumors. In terms of high rates of obesity, overall comorbidities, and obesity-related comorbidities, this report records major differences between Black and White women with early breast cancer and illustrates the prevalence of competing risks that may worsen outcomes in breast cancer.

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