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Obesity and risk of differentiated thyroid cancer: A large-scale case-control study

Clinical Endocrinology Oct 09, 2019

He Q, et al. - Researchers conducted a large frequency-matched case-control study based on hospital data to explore the connection between anthropometric measurements and risk of differentiated thyroid cancer (DTC). Participants in the study were 10,668 patients with DTC as well as 11,858 controls. According to univariate analysis, a significant increase in DTC risk with increased height, weight, BMI, body surface area (BSA), and body fat percentage (BF%), were recorded. In addition, the multivariate analysis displayed a positive correlation. The authors discovered that BF% remained significant only for women under 50 years of age, however, for both genders over age 50, neither BSA nor BF% was significantly linked to DTC risk. BF%, but not BMI, displayed a significant relationship with DTC risk for men under age 50. The risk of DTC, which was potentially affected by age and gender, was positively associated with BMI, BSA, and BF%.
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