Locke JE, et al. - Data from the Scientific Registry of Transplant Recipients were linked to data from the Centers for Medicare and Medicaid Services in order to study the association of being obese at the time of kidney donation with long-term mortality risk among 119,769 live kidney donors (1987–2013). For a maximum of 20 years, researchers followed the donors. Male, African American, and those with higher blood pressure more frequently comprised obese (body mass index ≥ 30) living kidney donors. Obese living kidney donors exhibit a 30% increased risk of long-term mortality compared with their nonobese counterparts after adjusting for age, sex, race/ethnicity, blood pressure, baseline estimated glomerular filtration rate, relationship to recipient, smoking, and year of donation. These findings may aid in selecting donors and discussions with obese persons considering living kidney donation.