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Obese- and allergic-related asthma phenotypes among children across the United States

Journal of Asthma May 03, 2019

Ross MK, et al. - Using data from the 2007–2008 National Survey of Children's Health, researchers evaluated the national prevalence, risk factors, and caregiver-reported severity of four asthma phenotypes (not-allergic-not-obese, allergic-not-obese, obese-not-allergic, and allergic-and-obese) across the United States. Overall 4427 children with asthma were included. Half of the studied asthma phenotypes included allergic-not-obese asthma, while one-fifth of asthma phenotypes encompassed obesity-related asthma (with or without allergic components). Allergic-not-obese asthma was most likely to be seen in white children with asthma while the likelihood of having obese-nonallergic phenotype was most frequently reported among while black and Hispanic children with asthma. Allergic-not-obese children were more susceptible to develop attention-deficit disorder/attention-deficit hyperactivity disorder. The obese-and-allergic asthma phenotype had the highest risk for more severe vs mild asthma.
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