El-Ghammaz AMS, et al. - This study planned to illustrate the nutritional status of allogeneic hematopoietic stem cell transplantation (HSCT) recipients. During hospitalization and after discharge, allogeneic HSCT patients having high comorbidity index, developing prolonged fever, and experiencing ≥grade II acute gastrointestinal graft versus host disease (GI GVHD) suffered from worsening in their nutritional status. In addition, their survival was impacted by nutritional status at admission and day 180.

Methods

• This study subjected fifty patients undergoing allogeneic HSCT to nutritional status assessment by using the patient-generated subjective global assessment (PG-SGA) at initial admission, day 30 and day 180.

Results

• Results revealed malnutrition in two patients (4%) at admission, 36 (72%) at day 30, and 24 (48%) at day 180.
• Comorbidity index higher than 0 and fever lasting for more than 1 week had a significant impact on nutritional status (P = .004 and P = .006, respectively), at day 30.
• Comorbidity index higher than 0 and presence of ≥grade II acute gastrointestinal graft versus host disease (GI GVHD) significantly influenced nutritional status (P = .017 and P = .026, respectively), regarding day 180.
• As compared to malnourished patients, well-nourished patients at admission and day 180 had a significantly higher overall survival (OS).
• In multivariate analysis, a significant influence of nutritional status at admission and day 180 on OS was reported (P = .039 and P = .032, respectively).