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Nuclear factor-kappa B1 inhibits early apoptosis of glioma cells by promoting the expression of Bcl-2

OncoTargets and Therapy Sep 09, 2017

Yang TQ, et al. – The researchers applied quantitative real-time polymerase chain reaction in order to explore the expression level of nuclear factor-kappa B1 (NF-κB1) in human glioma tissues. They explained that the NF-κB1 overexpression inhibits early apoptosis of glioma cells and high expression of NF-κB1 promotes the expression of antiapoptotic gene Bcl-2. They provided a theoretical basis for antiapoptotic mechanism of tumor cells in association with NF- κB1.
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