Heerma van Voss MR, et al. – The significance of and mechanisms behind nuclear DEAD box protein 3 (DDX3) expression had been assessed in colorectal and breast cancer. Partially chromosome region maintenance 1 (CRM1)–mediated, nuclear DDX3 predicted worse survival in colorectal and breast cancer patients, putting it forward as a target for therapeutic intervention with DDX3 inhibitors under development in these cancer types.