Jonsson MH, Hommel A, Todorova L, et al. - This study was attempted to investigate whether biomarkers add beneficial information to an existing risk score for prediction of 30‐day mortality in patients suffering from out of hospital hip fractures. This prospective observational single centre study was conducted to investigate the correlation between plasma concentration of ninety‐two biomarkers at admission and 30‐day mortality using logistic regression adjusted for risk factors included in Nottingham Hip Fracture Score (NHFS). Researchers further assessed biomarkers correlated with the outcome in the adjusted analysis by calculating the net reclassification improvement and the alteration in area under the receiver operating characteristics curve relative to the NHFS. This study enrolled a total of 997 individuals. The research of this study demonstrate that adding Growth Differentiation Factor‐15 or CA‐125 to the Nottingham Hip Fracture Score enhances the discrimination with regard to prognosticating 30‐day mortality and may help to distinguish a subgroup of hip fracture patients with a particularly poor prognosis. The value of these biomarkers should be investigated in future research to validate clinical utility.