Ashrafi AH, Lai W, Gaffar S et al, et al. - Via performing this prospective observational study, researchers investigated the measures of biventricular function and surrogates of pulmonary vascular resistance that can be expected in relatively stable extremely premature neonates. In addition, they examined maturational changes in myocardial performance in this patient population. They divided 46 clinically stable extremely preterm newborns into 3 cohorts based on gestational age: cohort 1 (24^0/7 – 25^6/7 weeks), cohort 2 (26^0/7 – 27^6/7 weeks), and cohort 3 (28^0/7 – 29^6/7 weeks). Observations revealed significant differences in terms of biventricular systolic performance between the clinically stable extremely premature neonate and healthy full-term newborns. Poor biventricular compliance was observed in all participants at birth which improved with maturation. There appeared no adverse effect of extreme prematurity on myocardial functional maturation at the time of term corrected age and/or discharge.