Moores M, Yogendrakumar V, Bereznyakova O, et al. - Researchers evaluated patients who presented with acute ischemic stroke within 12 hours of symptom onset at a comprehensive stroke center (January 2015 to December 2017) to determine whether cardioembolic etiology could be predicted by normotension at presentation with acute ischemic stroke. Systolic blood pressure ≤ 130 mmHg defined normotension. Blood pressure on entry at the hospital was the primary exposure, and cardioembolic etiology was the primary outcome. The investigators noted an inverse link between the likelihood of cardioembolic etiology and systolic blood pressure, as well as a significant link between initial systolic blood pressure and cardioembolic etiology. They observed a 2.62-fold increased odds of cardioembolic etiology in relation to normotension. In this study, normotension at presentation with acute ischemic stroke was identified as a strong predictor of cardioembolic etiology. Early and prolonged cardiac investigations may thus benefit this patient population.