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Normal gamma glutamyl transferase levels at presentation predict poor outcome in biliary atresia

Journal of Pediatric Gastroenterology and Nutrition Mar 05, 2020

Shankar S, Bolia R, Foo HW, et al. - In the present study, the researchers sought to characterize outcomes of a single-centre Australian cohort of infants with biliary atresia (BA) and evaluate the effect of gamma-glutamyl transferase levels (GGT) level at presentation on outcomes in BA. Infants diagnosed with BA between 1991 and 2017 have been retrospectively analyzed. At a median of 61 (30–149) days, 113 infants underwent Kasai portoenterostomy (KPE). Age at KPE and time to clearance of jaundice were comparable between normal and high GGT groups. According to findings, 12.3% of infants with BA were diagnosed with normal GGT levels. At presentation, low GGT levels in BA was linked to a poorer outcome.
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